A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer

The N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) mouse model is an attractive model system of muscle-invasive bladder cancer (MIBC) as it recapitulates the histology of human tumors in a background with intact immune system. However, it was unknown whether this carcinogen-induced model also mimicked...

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Detalles Bibliográficos
Autores principales: Fantini, Damiano, Glaser, Alexander P., Rimar, Kalen J., Wang, Yiduo, Schipma, Matthew, Varghese, Nobish, Rademaker, Alfred, Behdad, Amir, Yellapa, Aparna, Yu, Yanni, Sze, Christie Ching-Lin, Wang, Lu, Zhao, Zibo, Crawford, Susan E., Hu, Deqing, Licht, Jonathan D., Collings, Clayton K., Bartom, Elizabeth, Theodorescu, Dan, Shilatifard, Ali, Meeks, Joshua J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886988/
https://www.ncbi.nlm.nih.gov/pubmed/29367767
http://dx.doi.org/10.1038/s41388-017-0099-6

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