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Methyl donor deficient diets cause distinct alterations in lipid metabolism but are poorly representative of human NAFLD
Background: Non-alcoholic fatty liver disease (NAFLD) is a global health issue. Dietary methyl donor restriction is used to induce a NAFLD/non-alcoholic steatohepatitis (NASH) phenotype in rodents, however the extent to which this model reflects human NAFLD remains incompletely understood. To addres...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887079/ https://www.ncbi.nlm.nih.gov/pubmed/29707653 http://dx.doi.org/10.12688/wellcomeopenres.12199.1 |