Methyl donor deficient diets cause distinct alterations in lipid metabolism but are poorly representative of human NAFLD

Background: Non-alcoholic fatty liver disease (NAFLD) is a global health issue. Dietary methyl donor restriction is used to induce a NAFLD/non-alcoholic steatohepatitis (NASH) phenotype in rodents, however the extent to which this model reflects human NAFLD remains incompletely understood. To addres...

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Detalles Bibliográficos
Autores principales: Lyall, Marcus J., Cartier, Jessy, Richards, James A, Cobice, Diego, Thomson, John P, Meehan, Richard R, Anderton, Stephen M, Drake, Amanda J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887079/
https://www.ncbi.nlm.nih.gov/pubmed/29707653
http://dx.doi.org/10.12688/wellcomeopenres.12199.1

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