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A Reassessment of Genes Modulating Aging in Mice Using Demographic Measurements of the Rate of Aging
Many studies have reported genetic interventions that have an effect on mouse life span; however, it is crucial to discriminate between manipulations of aging and aging-independent causes of life extension. Here, we used the Gompertz equation to determine whether previously reported aging-related mo...
Autores principales: | Pedro de Magalhães, João, Thompson, Louise, de Lima, Izabella, Gaskill, Dale, Li, Xiaoyu, Thornton, Daniel, Yang, Chenhao, Palmer, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887152/ https://www.ncbi.nlm.nih.gov/pubmed/29444805 http://dx.doi.org/10.1534/genetics.118.300821 |
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