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Measuring DNA hybridization using fluorescent DNA-stabilized silver clusters to investigate mismatch effects on therapeutic oligonucleotides

BACKGROUND: Short nucleic acid oligomers have found a wide range of applications in experimental physics, biology and medicine, and show potential for the treatment of acquired and genetic diseases. These applications rely heavily on the predictability of hybridization through Watson–Crick base pair...

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Detalles Bibliográficos
Autores principales:	de Bruin, Donny, Bossert, Nelli, Aartsma-Rus, Annemieke, Bouwmeester, Dirk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887185/ https://www.ncbi.nlm.nih.gov/pubmed/29622040 http://dx.doi.org/10.1186/s12951-018-0361-2

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