Cargando…
Ghrelin therapy mitigates bone marrow injury and splenocytopenia by sustaining circulating G-CSF and KC increases after irradiation combined with wound
BACKGROUND: Radiation injury combined wound (CI) enhances acute radiation syndrome and subsequently mortality as compared to radiation injury alone (RI). We previously reported that ghrelin (a 28-amino-acid-peptide secreted from the stomach) treatment significantly increased a 30-day survival, mitig...
Autores principales: | Kiang, Juliann G., Anderson, Marsha N., Smith, Joan T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887249/ https://www.ncbi.nlm.nih.gov/pubmed/29632660 http://dx.doi.org/10.1186/s13578-018-0225-3 |
Ejemplares similares
-
Co-Therapy of Pegylated G-CSF and Ghrelin for Enhancing Survival After Exposure to Lethal Radiation
por: Kiang, Juliann G., et al.
Publicado: (2021) -
Ghrelin, a novel therapy, corrects cytokine and NF-κB-AKT-MAPK network and mitigates intestinal injury induced by combined radiation and skin-wound trauma
por: Kiang, Juliann G., et al.
Publicado: (2020) -
Ghrelin Therapy Improves Survival after Whole-Body Ionizing Irradiation or Combined with Burn or Wound: Amelioration of Leukocytopenia, Thrombocytopenia, Splenomegaly, and Bone Marrow Injury
por: Kiang, Juliann G., et al.
Publicado: (2014) -
Bone Marrow Mesenchymal Stem Cells Increase Survival after Ionizing Irradiation Combined with Wound Trauma: Characterization and Therapy
por: Kiang, Juliann G, et al.
Publicado: (2014) -
Ghrelin Therapy Decreases Incidents of Intracranial Hemorrhage in Mice after Whole-Body Ionizing Irradiation Combined with Burn Trauma
por: Gorbunov, Nikolai V., et al.
Publicado: (2017)