CCL17 blockade as a therapy for osteoarthritis pain and disease

BACKGROUND: Granulocyte macrophage-colony stimulating factor (GM-CSF) has been implicated in the pathogenesis of a number of inflammatory diseases and in osteoarthritis (OA). We identified previously a new GM-CSF→Jmjd3→interferon regulatory factor 4 (IRF4)→chemokine (c-c motif) ligand 17 (CCL17) pat...

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Detalles Bibliográficos
Autores principales: Lee, Ming-Chin, Saleh, Reem, Achuthan, Adrian, Fleetwood, Andrew J., Förster, Irmgard, Hamilton, John A., Cook, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887260/
https://www.ncbi.nlm.nih.gov/pubmed/29622035
http://dx.doi.org/10.1186/s13075-018-1560-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887260/
https://www.ncbi.nlm.nih.gov/pubmed/29622035
http://dx.doi.org/10.1186/s13075-018-1560-9

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