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Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA

Canonical bacterial transcription activators bind to non-transcribed promoter elements to increase transcription of their target genes. Here we report crystal structures of binary complexes comprising domains of Caulobacter crescentus GcrA, a noncanonical bacterial transcription factor, that support...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoxian, Haakonsen, Diane L, Sanderlin, Allen G, Liu, Yue J, Shen, Liqiang, Zhuang, Ningning, Laub, Michael T, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887438/
https://www.ncbi.nlm.nih.gov/pubmed/29514271
http://dx.doi.org/10.1093/nar/gky161