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Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment
Tumour necrosis factor (TNF) is produced by primary human macrophages in response to stimulation by exogenous pathogen-associated molecular patterns (PAMPs) and endogenous damage-associated molecular patterns (DAMPs) via Toll-like receptor (TLR) signalling. However, uncontrolled TNF production can b...
Autores principales: | Page, Theresa H., Urbaniak, Anna M., Espirito Santo, Ana I., Danks, Lynett, Smallie, Timothy, Williams, Lynn M., Horwood, Nicole J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887515/ https://www.ncbi.nlm.nih.gov/pubmed/29567473 http://dx.doi.org/10.1016/j.bbrc.2018.03.140 |
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