Cargando…
S193. EX VIVO SIGNATURE OF PSYCHOSIS AND TREATMENT RESPONSE IN PATIENT-DERIVED NEURONS
BACKGROUND: Postmortem studies in schizophrenia show well-replicated neuronal differences in the prefrontal cortex (PFC), specifically showing lower dendritic spine density in upper-layer cortical pyramidal neurons. Animal models that recapitulate features of psychosis also show lower dendritic spin...
Autores principales: | Karmacharya, Rakesh, Watmuff, Bradley, Kathuria, Annie, Liu, Bangyan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887660/ http://dx.doi.org/10.1093/schbul/sby018.980 |
Ejemplares similares
-
Morphological and transcriptomic analyses of stem cell-derived cortical neurons reveal mechanisms underlying synaptic dysfunction in schizophrenia
por: Kathuria, Annie, et al.
Publicado: (2023) -
Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine
por: Kathuria, Annie, et al.
Publicado: (2019) -
Disease-specific differences in gene expression, mitochondrial function and mitochondria-endoplasmic reticulum interactions in iPSC-derived cerebral organoids and cortical neurons in schizophrenia and bipolar disorder
por: Kathuria, Annie, et al.
Publicado: (2023) -
In Vitro Maturation of Dopaminergic Neurons Derived from Mouse Embryonic Stem Cells: Implications for Transplantation
por: Watmuff, Bradley, et al.
Publicado: (2012) -
AB193. Rectourethral fistula
por: Jiang, Hai
Publicado: (2016)