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Hepatocyte‐induced CD4(+) T cell alloresponse is associated with major histocompatibility complex class II up‐regulation on hepatocytes and suppressible by regulatory T cells
Hepatocyte transplantation is a promising therapeutic approach for various liver diseases. Despite the liver's tolerogenic potential, early immune‐mediated loss of transplanted cells is observed, and longterm acceptance has not been achieved yet. Patients deemed tolerant after liver transplanta...
Autores principales: | DeTemple, Daphne E., Oldhafer, Felix, Falk, Christine S., Chen‐Wacker, Chen, Figueiredo, Constanca, Kleine, Moritz, Ramackers, Wolf, Timrott, Kai, Lehner, Frank, Klempnauer, Juergen, Bock, Michael, Vondran, Florian W. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887891/ https://www.ncbi.nlm.nih.gov/pubmed/29365365 http://dx.doi.org/10.1002/lt.25019 |
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