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Increased hyperpolarized [1‐(13)C] lactate production in a model of joint inflammation is not accompanied by tissue acidosis as assessed using hyperpolarized (13)C‐labelled bicarbonate

Arthritic conditions are a major source of chronic pain. Furthering our understanding of disease mechanisms creates the opportunity to develop more targeted therapeutics. In rheumatoid arthritis (RA), measurements of pH in human synovial fluid suggest that acidosis occurs, but that this is highly va...

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Detalles Bibliográficos
Autores principales:	Wright, Alan J., Husson, Zoé M.A., Hu, De‐En, Callejo, Gerard, Brindle, Kevin M., Smith, Ewan St. John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887936/ https://www.ncbi.nlm.nih.gov/pubmed/29380927 http://dx.doi.org/10.1002/nbm.3892

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