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14.2 STUCTURED RISK ASSESSMENT IN PSYCHIATRY

BACKGROUND: Current approaches to stratify psychiatric patients into groups based on violence risk are limited by inconsistency, variable accuracy, and unscalability. METHODS: Based on a national cohort of 75 158 Swedish individuals aged 15–65 with a diagnosis of severe mental illness (schizophrenic...

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Autores principales: Fazel, Seena, Wolf, Achim, Larsson, Henrik, Fanshawe, Thomas, Mallett, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887983/
http://dx.doi.org/10.1093/schbul/sby014.055
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author Fazel, Seena
Wolf, Achim
Larsson, Henrik
Fanshawe, Thomas
Mallett, Susan
author_facet Fazel, Seena
Wolf, Achim
Larsson, Henrik
Fanshawe, Thomas
Mallett, Susan
author_sort Fazel, Seena
collection PubMed
description BACKGROUND: Current approaches to stratify psychiatric patients into groups based on violence risk are limited by inconsistency, variable accuracy, and unscalability. METHODS: Based on a national cohort of 75 158 Swedish individuals aged 15–65 with a diagnosis of severe mental illness (schizophrenic-spectrum and bipolar disorders) with 574 018 patient episodes, we developed predictive models for violent offending through linkage of population-based registers. First, a derivation model was developed to determine strength of pre-specified criminal history, socio-demographic, and clinical risk factors, and tested it in external validation. We measured discrimination and calibration for prediction of violent offending at 1 year using specified risk cut-offs. RESULTS: A 16 item model was developed from criminal history, socio-demographic and clinical risk factors, which are mostly routinely collected. In external validation, the model showed good measures of discrimination (c-index 0.89) and calibration. For risk of violent offending at 1 year, using a 5% cut off, sensitivity was 64% and specificity was 94%. Positive and negative predictive values were 11% and 99%, respectively. The model was used to generate a simple web-based risk calculator (OxMIV). DISCUSSION: We have developed a prediction score in a national cohort of patients with psychosis that can be used as an adjunct to decision making in clinical practice by identifying those who are at low risk of violent offending
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spelling pubmed-58879832018-04-11 14.2 STUCTURED RISK ASSESSMENT IN PSYCHIATRY Fazel, Seena Wolf, Achim Larsson, Henrik Fanshawe, Thomas Mallett, Susan Schizophr Bull Abstracts BACKGROUND: Current approaches to stratify psychiatric patients into groups based on violence risk are limited by inconsistency, variable accuracy, and unscalability. METHODS: Based on a national cohort of 75 158 Swedish individuals aged 15–65 with a diagnosis of severe mental illness (schizophrenic-spectrum and bipolar disorders) with 574 018 patient episodes, we developed predictive models for violent offending through linkage of population-based registers. First, a derivation model was developed to determine strength of pre-specified criminal history, socio-demographic, and clinical risk factors, and tested it in external validation. We measured discrimination and calibration for prediction of violent offending at 1 year using specified risk cut-offs. RESULTS: A 16 item model was developed from criminal history, socio-demographic and clinical risk factors, which are mostly routinely collected. In external validation, the model showed good measures of discrimination (c-index 0.89) and calibration. For risk of violent offending at 1 year, using a 5% cut off, sensitivity was 64% and specificity was 94%. Positive and negative predictive values were 11% and 99%, respectively. The model was used to generate a simple web-based risk calculator (OxMIV). DISCUSSION: We have developed a prediction score in a national cohort of patients with psychosis that can be used as an adjunct to decision making in clinical practice by identifying those who are at low risk of violent offending Oxford University Press 2018-04 2018-04-01 /pmc/articles/PMC5887983/ http://dx.doi.org/10.1093/schbul/sby014.055 Text en © Maryland Psychiatric Research Center 2018. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstracts
Fazel, Seena
Wolf, Achim
Larsson, Henrik
Fanshawe, Thomas
Mallett, Susan
14.2 STUCTURED RISK ASSESSMENT IN PSYCHIATRY
title 14.2 STUCTURED RISK ASSESSMENT IN PSYCHIATRY
title_full 14.2 STUCTURED RISK ASSESSMENT IN PSYCHIATRY
title_fullStr 14.2 STUCTURED RISK ASSESSMENT IN PSYCHIATRY
title_full_unstemmed 14.2 STUCTURED RISK ASSESSMENT IN PSYCHIATRY
title_short 14.2 STUCTURED RISK ASSESSMENT IN PSYCHIATRY
title_sort 14.2 stuctured risk assessment in psychiatry
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887983/
http://dx.doi.org/10.1093/schbul/sby014.055
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