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27.4 STRUCTURAL, FUNCTIONAL, AND BEHAVIORAL INSIGHTS OF DOPAMINE DYSFUNCTION REVEALED BY A DELETION IN SLC6A3

BACKGROUND: The human dopamine (DA) transporter (hDAT) mediates clearance of DA. Genetic variants in hDAT are associated to neuropsychiatric disorders. We investigated the structural and behavioral bases of an in-frame deletion in hDAT at N336 (∆N336) associated with neuropsychiatric disorders. METH...

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Detalles Bibliográficos
Autor principal: Galli, Aurelio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888004/
http://dx.doi.org/10.1093/schbul/sby014.114

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