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Systems assessment of transcriptional regulation on central carbon metabolism by Cra and CRP

Two major transcriptional regulators of carbon metabolism in bacteria are Cra and CRP. CRP is considered to be the main mediator of catabolite repression. Unlike for CRP, in vivo DNA binding information of Cra is scarce. Here we generate and integrate ChIP-exo and RNA-seq data to identify 39 binding...

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Detalles Bibliográficos
Autores principales: Kim, Donghyuk, Seo, Sang Woo, Gao, Ye, Nam, Hojung, Guzman, Gabriela I, Cho, Byung-Kwan, Palsson, Bernhard O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888115/
https://www.ncbi.nlm.nih.gov/pubmed/29394395
http://dx.doi.org/10.1093/nar/gky069