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CXCL4 is a novel inducer of human Th17 cells and correlates with IL‐17 and IL‐22 in psoriatic arthritis

CXCL4 regulates multiple facets of the immune response and is highly upregulated in various Th17‐associated rheumatic diseases. However, whether CXCL4 plays a direct role in the induction of IL‐17 production by human CD4(+) T cells is currently unclear. Here, we demonstrated that CXCL4 induced human...

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Detalles Bibliográficos
Autores principales: Affandi, Alsya J., Silva‐Cardoso, Sandra C., Garcia, Samuel, Leijten, Emmerik F. A., van Kempen, Tessa S., Marut, Wioleta, van Roon, Joel A. G., Radstake, Timothy R. D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888178/
https://www.ncbi.nlm.nih.gov/pubmed/29193036
http://dx.doi.org/10.1002/eji.201747195