Cargando…
T221. LURASIDONE DISPLAYS ANTIDEPRESSANT AND PRO-COGNITIVE EFFECTS IN THE CHRONIC MILD STRESS MODEL: A ROLE FOR REDOX MECHANISMS AND PARVALBUMIN EXPRESSION
BACKGROUND: Exposure of rodents to chronic stress is able to recapitulate a number of functional alterations that are associated with psychiatric disorders, including anhedonia and cognitive impairment. Stress-based experimental models are also useful to investigate the ability of pharmacological in...
Autores principales: | Rossetti, Andrea Carlo, Paladini, Maria Serena, Brivio, Paola, Sbrini, Giulia, Papp, Mariusz, Calabrese, Francesca, Molteni, Raffaella, Riva, Marco Andrea |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888300/ http://dx.doi.org/10.1093/schbul/sby016.497 |
Ejemplares similares
-
Chronic Stress Exposure Reduces Parvalbumin Expression in the Rat Hippocampus through an Imbalance of Redox Mechanisms: Restorative Effect of the Antipsychotic Lurasidone
por: Rossetti, Andrea C, et al.
Publicado: (2018) -
Altered responsiveness of the antioxidant system in chronically stressed animals: modulation by chronic lurasidone treatment
por: Spero, Vittoria, et al.
Publicado: (2022) -
Lurasidone Exerts Antidepressant Properties in the Chronic Mild Stress Model through the Regulation of Synaptic and Neuroplastic Mechanisms in the Rat Prefrontal Cortex
por: Luoni, Alessia, et al.
Publicado: (2015) -
Stress Modifies the Expression of Glucocorticoid-Responsive Genes by Acting at Epigenetic Levels in the Rat Prefrontal Cortex: Modulatory Activity of Lurasidone
por: Brivio, Paola, et al.
Publicado: (2021) -
Involvement of the IL-6 Signaling Pathway in the Anti-Anhedonic Effect of the Antidepressant Agomelatine in the Chronic Mild Stress Model of Depression
por: Rossetti, Andrea C., et al.
Publicado: (2022)