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O1.8. STRESS-INDUCED AMYGDALA HYPERACTIVITY LEADS TO INTERNEURON LOSS AND SCHIZOPHRENIA-LIKE PATHOLOGY IN A DEVELOPMENTAL DISRUPTION MODEL OF SCHIZOPHRENIA
BACKGROUND: Studies of the MAM rat model of schizophrenia show that rats exhibit higher anxiety levels, greater response to stress, and amygdala hyperactivity prepubertally before the emergence of the hyperdopaminergic state later in life. Furthermore, administration of diazepam prepubertally preven...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888303/ http://dx.doi.org/10.1093/schbul/sby015.190 |