Cargando…

F44. AN ADD-ON TRIAL WITH N-ACETYL-CYSTEINE (NAC) IN EARLY PSYCHOSIS PATIENTS: TOWARDS BIOMARKER GUIDED TREATMENT

BACKGROUND: Oxidative stress, coupled with dysregulation of inflammation, NMDAR and dopamine, is involved in schizophrenia (SZ) pathophysiology. Earlier add-on clinical trials showed in chronic SZ patients that NAC, a precursor of glutathione (GSH), an important cerebral antioxidant, improved negati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Conus, Philippe, Fournier, Margot, Xin, Lijing, Cleusix, Martine, Baumann, Philipp S, Ferrari, Carina, Cousins, Ann, Alameda, Luis, Gholam-Razaee, Mehdi, Golay, Philippe, Jenni, Raoul, Woo, Tsung-Ung Wilson, Keshavan, Matcheri, Eap, Chin B, Wojcik, Joanne, Cuenod, Michel, Buclin, Thierry, Gruetter, Rolf, Seidman, Larry, Do, Kim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888404/ http://dx.doi.org/10.1093/schbul/sby017.575

Ejemplares similares

N-acetylcysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis
por: Conus, Philippe, et al.
Publicado: (2018)

T52. N-ACETYL-CYSTEINE ADD-ON TREATMENT LEADS TO AN IMPROVEMENT OF FORNIX WHITE MATTER INTEGRITY IN EARLY PSYCHOSIS
por: Klauser, Paul, et al.
Publicado: (2018)

N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial
por: Klauser, Paul, et al.
Publicado: (2018)

Topology predicts long-term functional outcome in early psychosis
por: Fournier, Margot, et al.
Publicado: (2020)

M16. PROFILING GLUTAMATE AND D-SERINE PATHWAYS IN TREATMENT RESISTANT EARLY PSYCHOSIS PATIENTS
por: Camporesi, Sara, et al.
Publicado: (2020)

16.2 CHILDHOOD TRAUMA ENGAGES OXIDATIVE STRESS, HIPPOCAMPUS ALTERATIONS, AND POORER CLINICAL OUTCOME IN EARLY PSYCHOSIS PATIENTS
por: Alameda, Luis, et al.
Publicado: (2018)

N-Acetyl-Cysteine Supplementation Improves Functional Connectivity Within the Cingulate Cortex in Early Psychosis: A Pilot Study
por: Mullier, Emeline, et al.
Publicado: (2019)

F227. PSYCHOLOGICAL TRAUMA OCCURRING DURING ADOLESCENCE IS ASSOCIATED WITH AN INCREASED RISK OF GREATER WAIST CIRCUMFERENCE IN EARLY PSYCHOSIS PATIENTS INDEPENDENTLY OF MEDICATION
por: Alameda, Luis, et al.
Publicado: (2018)

Timely N-Acetyl-Cysteine and Environmental Enrichment Rescue Oxidative Stress-Induced Parvalbumin Interneuron Impairments via MMP9/RAGE Pathway: A Translational Approach for Early Intervention in Psychosis
por: Dwir, Daniella, et al.
Publicado: (2021)

10.2 REDOX DYSREGULATION, OLIGODENDROCYTES AND WHITE MATTER ALTERATIONS IN SCHIZOPHRENIA
por: Klauser, Paul, et al.
Publicado: (2018)

Characterization of early psychosis patients carrying a genetic vulnerability to redox dysregulation: a computational analysis of mechanism-based gene expression profile in fibroblasts
por: Giangreco, Basilio, et al.
Publicado: (2023)

Redox dysregulation as a link between childhood trauma and psychopathological and neurocognitive profile in patients with early psychosis
por: Alameda, Luis, et al.
Publicado: (2018)

Early onset of cannabis use and violent behavior in psychosis
por: Moulin, Valerie, et al.
Publicado: (2020)

Evolution of impulsivity levels in relation to early cannabis use in violent patients in the early phase of psychosis
por: Dan-Glauser, Elise, et al.
Publicado: (2023)

Psychological trauma occurring during adolescence is associated with an increased risk of greater waist circumference in Early Psychosis patients treated with psychotropic medication
por: Alameda, Luis, et al.
Publicado: (2020)

Time of exposure to social defeat stress during childhood and adolescence and redox dysregulation on long-lasting behavioral changes, a translational study
por: Schnider, Mirko, et al.
Publicado: (2022)

Prevalence of ECG abnormalities and risk factors for QTc interval prolongation in hospitalized psychiatric patients
por: Ansermot, Nicolas, et al.
Publicado: (2019)

Impaired fornix–hippocampus integrity is linked to peripheral glutathione peroxidase in early psychosis
por: Baumann, P S, et al.
Publicado: (2016)

Internal and Predictive Validity of the French Health of the Nation Outcome Scales: Need for Future Directions
por: Golay, Philippe, et al.
Publicado: (2016)

Bridging structural MRI with cognitive function for individual level classification of early psychosis via deep learning
por: Wen, Yang, et al.
Publicado: (2023)

MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia patients
por: Dwir, Daniella, et al.
Publicado: (2019)

S180. MICROSTRUCTURE COMPLEXITY OF THE THALAMUS IN SCHIZOPHRENIA: A NODDI STUDY
por: Alemán-Gómez, Yasser, et al.
Publicado: (2018)

Dynamics between insight and medication adherence in first-episode psychosis: Study of 3-year trajectories
por: Elowe, Julien, et al.
Publicado: (2022)

S164. “AT-RISK MENTAL STATES” PROGRAM IN LAUSANNE: INFLUENCE OF RECRUITMENT STRATEGIES ON THE RATE OF FALSE POSITIVES
por: Solida, Alessandra, et al.
Publicado: (2018)

Insight as a social identity process in the evolution of psychosocial functioning in the early phase of psychosis
por: Klaas, H. S., et al.
Publicado: (2017)

Mitochondrial, exosomal miR137-COX6A2 and gamma synchrony as biomarkers of parvalbumin interneurons, psychopathology, and neurocognition in schizophrenia
por: Khadimallah, Ines, et al.
Publicado: (2021)

The Potential of N-Acetyl-L-Cysteine (NAC) in the Treatment of Psychiatric Disorders
por: Bradlow, Richard C. J., et al.
Publicado: (2022)

Pandemics and psychiatry: Repositioning research in context of COVID-19
por: Keshavan, Matcheri S.
Publicado: (2020)

Building resilience in the COVID-19 era: Three paths in the Bhagavad Gita
por: Keshavan, Matcheri S.
Publicado: (2020)

Psychotropic drug-induced genetic-epigenetic modulation of CRTC1 gene is associated with early weight gain in a prospective study of psychiatric patients
por: Delacrétaz, Aurélie, et al.
Publicado: (2019)

Metabolomic alteration induced by psychotropic drugs: Short‐term metabolite profile as a predictor of weight gain evolution
por: Lenski, Marie, et al.
Publicado: (2021)

Correction to: The Potential of N‑Acetyl‑L‑Cysteine (NAC) in the Treatment of Psychiatric Disorders
por: Bradlow, Richard C. J., et al.
Publicado: (2022)

The Efficacy of N-Acetyl-Cysteine (NAC) Supplementation in FST Model for Screening Antidepressants
por: Memudu, Adejoke Elizabeth
Publicado: (2022)

S69. CLINICAL HIGH RISK STATE: STRATIFICATION BASED ON CLINICAL PROFILE AND REDOX STATUS
por: Cleusix, Martine, et al.
Publicado: (2020)

City Avoidance in the Early Phase of Psychosis: A Neglected Domain of Assessment and a Potential Target for Recovery Strategies
por: Conus, Philippe, et al.
Publicado: (2019)

Cannabis, a Significant Risk Factor for Violent Behavior in the Early Phase Psychosis. Two Patterns of Interaction of Factors Increase the Risk of Violent Behavior: Cannabis Use Disorder and Impulsivity; Cannabis Use Disorder, Lack of Insight and Treatment Adherence
por: Moulin, Valerie, et al.
Publicado: (2018)

Cognitive Remediation in Schizophrenia
por: Kaneko, Yoshio, et al.
Publicado: (2012)

Biomarkers in Psychiatry - A Critique
por: Venkatasubramanian, Ganesan, et al.
Publicado: (2016)

Connectome development and a novel extension to the neurodevelopmental model of schizophrenia
por: Collin, Guusje, et al.
Publicado: (2018)

COVID-19, mobile health and serious mental illness
por: Torous, John, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_kp9fodjaegqe208p4t0ovi8t9q