Cargando…
O1.6. INCREASED COMPLEMENT FACTORS C3 AND C4 IN SCHIZOPHRENIA AND THE EARLY STAGES OF PSYCHOSIS: IMPLICATIONS FOR CLINICAL SYMPTOMATOLOGY AND CORTICAL THICKNESS
BACKGROUND: The complement system - a key component of the innate immune system, has been proposed to contribute to the pathogenesis of schizophrenia. Recently, complement C4 was associated with increased risk of schizophrenia, and in a mouse model, developmentally-timed synaptic pruning. These obse...
Autores principales: | Cropley, Vanessa, Laskaris, Liliana, Zalesky, Andrew, Weickert, Cynthia Shannon, Biase, Maria Di, Chana, Gursharan, Baune, Bernhard, Bousman, Chad, Nelson, Barnaby, McGorry, Patrick D, Everall, Ian, Pantelis, Christos |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888408/ http://dx.doi.org/10.1093/schbul/sby015.188 |
Ejemplares similares
-
PET imaging of putative microglial activation in individuals at ultra-high risk for psychosis, recently diagnosed and chronically ill with schizophrenia
por: Di Biase, M A, et al.
Publicado: (2017) -
Biomarker investigations related to pathophysiological pathways in schizophrenia and psychosis
por: Chana, Gursharan, et al.
Publicado: (2013) -
Peripheral Transcription of NRG-ErbB Pathway Genes Are Upregulated in Treatment-Resistant Schizophrenia
por: Mostaid, Md Shaki, et al.
Publicado: (2017) -
Elevated peripheral expression of neuregulin-1 (NRG1) mRNA isoforms in clozapine-treated schizophrenia patients
por: Mostaid, Md Shaki, et al.
Publicado: (2017) -
Elevated ubiquitinated proteins in brain and blood of individuals with schizophrenia
por: Bousman, Chad A., et al.
Publicado: (2019)