Cargando…
S187. SEARCHING FOR BRAIN CO-EXPRESSION MODULES THAT CONTRIBUTE DISPROPORTIONATELY TO THE COMMON POLYGENIC RISK FOR SCHIZOPHRENIA
BACKGROUND: Genomic research has revealed that schizophrenia is a highly polygenic disease. Recent estimates indicate that at least 71% of genomic segments of 1 Mb include one or more risk loci for schizophrenia (Loh et al., Nature Genet 2015). This extremely high polygenicity represents a challenge...
Autores principales: | Costas, Javier, Paramo, Mario, Arrojo, Manuel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888453/ http://dx.doi.org/10.1093/schbul/sby018.974 |
Ejemplares similares
-
Common variants in polygenic schizophrenia
por: Glessner, Joseph T, et al.
Publicado: (2009) -
Polygenic contribution to the relationship of loneliness and social isolation with schizophrenia
por: Andreu-Bernabeu, Álvaro, et al.
Publicado: (2022) -
F187. TBSS ANALYSIS OF WHITE MATTER ALTERATIONS IN SCHIZOPHRENIA PATIENTS VS. HEALTHY CONTROLS – RELATION TO AUDITORY VERBAL HALLUCINATIONS
por: Beresniewicz, Justyna, et al.
Publicado: (2018) -
20.4 MODELING THE CONTRIBUTION OF COMMON VARIANTS TO SCHIZOPHRENIA RISK
por: Hoffman, Gabriel, et al.
Publicado: (2018) -
Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood
por: Hatzimanolis, Alex, et al.
Publicado: (2015)