Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC

Dynamic changes in DNA methylation and demethylation reprogram transcriptional outputs to instruct lineage specification during development. Here, we applied an integrative epigenomic approach to unveil DNA (hydroxy)methylation dynamics representing major endodermal lineage intermediates during panc...

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Detalles Bibliográficos
Autores principales: Li, Jia, Wu, Xinwei, Zhou, Yubin, Lee, Minjung, Guo, Lei, Han, Wei, Mo, William, Cao, Wen-ming, Sun, Deqiang, Xie, Ruiyu, Huang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888657/
https://www.ncbi.nlm.nih.gov/pubmed/29394393
http://dx.doi.org/10.1093/nar/gky063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888657/
https://www.ncbi.nlm.nih.gov/pubmed/29394393
http://dx.doi.org/10.1093/nar/gky063

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