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Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC
Dynamic changes in DNA methylation and demethylation reprogram transcriptional outputs to instruct lineage specification during development. Here, we applied an integrative epigenomic approach to unveil DNA (hydroxy)methylation dynamics representing major endodermal lineage intermediates during panc...
Autores principales: | Li, Jia, Wu, Xinwei, Zhou, Yubin, Lee, Minjung, Guo, Lei, Han, Wei, Mo, William, Cao, Wen-ming, Sun, Deqiang, Xie, Ruiyu, Huang, Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888657/ https://www.ncbi.nlm.nih.gov/pubmed/29394393 http://dx.doi.org/10.1093/nar/gky063 |
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