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Are Nonsense Alleles of Drosophila melanogaster Genes under Any Selection?
A gene which carries a bona fide loss-of-function mutation effectively becomes a functionless pseudogene, free from selective constraint. However, there is a number of molecular mechanisms that may lead to at least a partial preservation of the function of genes carrying even drastic alleles. We per...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888714/ https://www.ncbi.nlm.nih.gov/pubmed/29425311 http://dx.doi.org/10.1093/gbe/evy032 |