Cargando…
Hedgehog signaling contributes to bone cancer pain by regulating sensory neuron excitability in rats
Treating bone cancer pain continues to be a clinical challenge and underlying mechanisms of bone cancer pain remain elusive. Here, we reported that sonic hedgehog signaling plays a critical role in the development of bone cancer pain. Tibia bone cavity tumor cell implantation produces bone cancer-re...
Autores principales: | Liu, Su, Lv, You, Wan, Xin-Xin, Song, Zhi-Jing, Liu, Yue-Peng, Miao, Shuai, Wang, Guang-Lei, Liu, Gong-Jian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888817/ https://www.ncbi.nlm.nih.gov/pubmed/29607715 http://dx.doi.org/10.1177/1744806918767560 |
Ejemplares similares
-
Sonic hedgehog signaling in spinal cord contributes to morphine-induced hyperalgesia and tolerance through upregulating brain-derived neurotrophic factor expression
por: Liu, Su, et al.
Publicado: (2018) -
Gastrodin Inhibits Allodynia and Hyperalgesia in Painful Diabetic Neuropathy Rats by Decreasing Excitability of Nociceptive Primary Sensory Neurons
por: Sun, Wei, et al.
Publicado: (2012) -
TRESK channel contribution to nociceptive sensory neurons excitability: modulation by nerve injury
por: Tulleuda, Astrid, et al.
Publicado: (2011) -
Sensory neuron–derived Na(V)1.7 contributes to dorsal horn neuron excitability
por: Alles, Sascha R. A., et al.
Publicado: (2020) -
Enhanced excitability of small dorsal root ganglion neurons in rats with bone cancer pain
por: Zheng, Qin, et al.
Publicado: (2012)