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Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells
Targeting tumor-initiating, drug-resistant populations of cancer stem cells (CSC) with phytochemicals is a novel paradigm for cancer prevention and treatment. We herein employed a phenotypic drug discovery approach coupled to mechanism-of-action profiling and target deconvolution to identify phenoli...
Autores principales: | Corominas-Faja, Bruna, Cuyàs, Elisabet, Lozano-Sánchez, Jesús, Cufí, Sílvia, Verdura, Sara, Fernández-Arroyo, Salvador, Borrás-Linares, Isabel, Martin-Castillo, Begoña, Martin, Ángel G, Lupu, Ruth, Nonell-Canals, Alfons, Sanchez-Martinez, Melchor, Micol, Vicente, Joven, Jorge, Segura-Carretero, Antonio, Menendez, Javier A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888987/ https://www.ncbi.nlm.nih.gov/pubmed/29452350 http://dx.doi.org/10.1093/carcin/bgy023 |
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