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Pertuzumab, trastuzumab, and standard anthracycline- and taxane-based chemotherapy for the neoadjuvant treatment of patients with HER2-positive localized breast cancer (BERENICE): a phase II, open-label, multicenter, multinational cardiac safety study
BACKGROUND: Anti-HER2 therapies are associated with a risk of increased cardiac toxicity, particularly when part of anthracycline-containing regimens. We report cardiac safety of pertuzumab, trastuzumab, and chemotherapy in the neoadjuvant treatment of HER2-positive early breast cancer. PATIENTS AND...
Autores principales: | Swain, S M, Ewer, M S, Viale, G, Delaloge, S, Ferrero, J -M, Verrill, M, Colomer, R, Vieira, C, Werner, T L, Douthwaite, H, Bradley, D, Waldron-Lynch, M, Kiermaier, A, Eng-Wong, J, Dang, C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888999/ https://www.ncbi.nlm.nih.gov/pubmed/29253081 http://dx.doi.org/10.1093/annonc/mdx773 |
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