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[PIN(+)]ing down the mechanism of prion appearance
Prions are conformationally flexible proteins capable of adopting a native state and a spectrum of alternative states associated with a change in the function of the protein. These alternative states are prone to assemble into amyloid aggregates, which provide a structure for self-replication and tr...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889010/ https://www.ncbi.nlm.nih.gov/pubmed/29718197 http://dx.doi.org/10.1093/femsyr/foy026 |