Cargando…

Prognostic markers for colorectal cancer: estimating ploidy and stroma

BACKGROUND: We report here the prognostic value of ploidy and digital tumour-stromal morphometric analyses using material from 2624 patients with early stage colorectal cancer (CRC). PATIENTS AND METHODS: DNA content (ploidy) and stroma-tumour fraction were estimated using automated digital imaging...

Descripción completa

Detalles Bibliográficos
Autores principales:	Danielsen, H E, Hveem, T S, Domingo, E, Pradhan, M, Kleppe, A, Syvertsen, R A, Kostolomov, I, Nesheim, J A, Askautrud, H A, Nesbakken, A, Lothe, R A, Svindland, A, Shepherd, N, Novelli, M, Johnstone, E, Tomlinson, I, Kerr, R, Kerr, D J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889021/ https://www.ncbi.nlm.nih.gov/pubmed/29293881 http://dx.doi.org/10.1093/annonc/mdx794

Ejemplares similares

Chromatin organisation and cancer prognosis: a pan-cancer study
por: Kleppe, Andreas, et al.
Publicado: (2018)

PTEN and DNA Ploidy Status by Machine Learning in Prostate Cancer
por: Cyll, Karolina, et al.
Publicado: (2021)

Prognostic impact of genomic instability in colorectal cancer
por: Hveem, T S, et al.
Publicado: (2014)

Association Between Proportion of Nuclei With High Chromatin Entropy and Prognosis in Gynecological Cancers
por: Nielsen, Birgitte, et al.
Publicado: (2018)

Prognostic value of mitotic checkpoint protein BUB3, cyclin B1, and pituitary tumor-transforming 1 expression in prostate cancer
por: Ersvær, Elin, et al.
Publicado: (2019)

Correction: Tumour-infiltrating CD8(+) lymphocytes and colorectal cancer recurrence by tumour and nodal stage
por: Glaire, Mark A., et al.
Publicado: (2019)

Tumour-infiltrating CD8(+) lymphocytes and colorectal cancer recurrence by tumour and nodal stage
por: Glaire, Mark A., et al.
Publicado: (2019)

Chromatin changes predict recurrence after radical prostatectomy
por: Hveem, Tarjei S, et al.
Publicado: (2016)

Automated assessment of CD8(+) T-lymphocytes and stroma fractions complement conventional staging of colorectal cancer
por: Jiang, Dan, et al.
Publicado: (2021)

Prognostic Significance of β-Catenin, E-Cadherin, and SOX9 in Colorectal Cancer: Results from a Large Population-Representative Series
por: Bruun, Jarle, et al.
Publicado: (2014)

Multilevel genomics of colorectal cancers with microsatellite instability—clinical impact of JAK1 mutations and consensus molecular subtype 1
por: Sveen, Anita, et al.
Publicado: (2017)

Prediction of relapse-free survival according to adjuvant chemotherapy and regulator of chromosome condensation 2 (RCC2) expression in colorectal cancer
por: Bergsland, Christian H, et al.
Publicado: (2020)

Microsatellite instability has a positive prognostic impact on stage II colorectal cancer after complete resection: results from a large, consecutive Norwegian series
por: Merok, M. A., et al.
Publicado: (2013)

DNA ploidy in curettage specimens identifies high-risk patients and lymph node metastasis in endometrial cancer
por: Njølstad, T S, et al.
Publicado: (2015)

CMS-dependent prognostic impact of KRAS and BRAF(V600E) mutations in primary colorectal cancer
por: Smeby, J, et al.
Publicado: (2018)

SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
por: Lind, G E, et al.
Publicado: (2011)

Stromal composition predicts recurrence of early rectal cancer after local excision
por: Jones, Helen J S, et al.
Publicado: (2021)

CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers
por: Vedeld, Hege Marie, et al.
Publicado: (2017)

The TP53 tumour suppressor gene in colorectal carcinomas. II. Relation to DNA ploidy pattern and clinicopathological variables.
por: Meling, G. I., et al.
Publicado: (1993)

Prognostic importance of DNA ploidy and DNA index in stage I and II endometrioid adenocarcinoma of the endometrium
por: Pradhan, M., et al.
Publicado: (2012)

Spatial analysis and CD25-expression identify regulatory T cells as predictors of a poor prognosis in colorectal cancer
por: Bergsland, Christian H., et al.
Publicado: (2022)

Genetic alterations within the retinoblastoma locus in colorectal carcinomas. Relation to DNA ploidy pattern studied by flow cytometric analysis.
por: Meling, G. I., et al.
Publicado: (1991)

Histopathological grading and DNA ploidy as prognostic markers in metastatic prostatic cancer.
por: Jørgensen, T., et al.
Publicado: (1995)

Phospholipase C Isozymes Are Deregulated in Colorectal Cancer – Insights Gained from Gene Set Enrichment Analysis of the Transcriptome
por: Danielsen, Stine A., et al.
Publicado: (2011)

Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2
por: Lopes, Nair, et al.
Publicado: (2019)

Prognostic value of nucleotyping, DNA ploidy and stroma in high-risk stage II colon cancer
por: Yang, Lujing, et al.
Publicado: (2020)

Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series
por: Domingo, Enric, et al.
Publicado: (2018)

Use of multivariate analysis to suggest a new molecular classification of colorectal cancer
por: Domingo, Enric, et al.
Publicado: (2013)

Re-assessing ZNF331 as a DNA methylation biomarker for colorectal cancer
por: Vedeld, Hege Marie, et al.
Publicado: (2018)

Tumour ploidy, response and survival in patients receiving endocrine therapy for advanced breast cancer.
por: Stuart-Harris, R., et al.
Publicado: (1985)

Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains
por: Berg, Kaja C. G., et al.
Publicado: (2019)

DNA ploidy may be a prognostic marker in stage I and II serous adenocarcinoma of the endometrium
por: Pradhan, Manohar, et al.
Publicado: (2012)

A Tissue-Based Comparative Effectiveness Analysis of Biomarkers for Early Detection of Colorectal Tumors
por: Ahmed, Deeqa, et al.
Publicado: (2012)

Flow cytometric analysis of ploidy in colorectal cancer: a multicentric experience.
por: Silvestrini, R., et al.
Publicado: (1993)

Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer
por: Eilertsen, Ina A., et al.
Publicado: (2018)

Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas
por: Lind, Guro E, et al.
Publicado: (2011)

Transcriptional and functional consequences of TP53 splice mutations in colorectal cancer
por: Smeby, Jørgen, et al.
Publicado: (2019)

Epigenetic and genetic features of 24 colon cancer cell lines
por: Ahmed, D, et al.
Publicado: (2013)

Clinical utility of chromatin analysis
por: Kleppe, Andreas, et al.
Publicado: (2018)

E‐cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
por: Bruun, Jarle, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lh4u2id5hbgi5cfp1qui0tlma4