Angioimmunoblastic T‐cell lymphoma: a rare subtype of peripheral T‐cell lymphoma

Angioimmunoblastic T‐cell lymphoma (AITL) is a rare form of NHL and usually presents in the late stage due to the atypical laboratory findings. Immunohistochemistry of the lymph node in AITL is characterized by positive CD2, CD3, CD4, CD10, CXCL‐13, PD1 often BCL‐6 and CD20 positive. Meshworks of fo...

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Detalles Bibliográficos
Autores principales: Rai, Manoj Ponadka, Bedi, Prabhjot Singh, Marinas, Edwin B, Khan, Nazia Naz S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Clinical Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889216/
https://www.ncbi.nlm.nih.gov/pubmed/29636953
http://dx.doi.org/10.1002/ccr3.1388
Descripción
Sumario:Angioimmunoblastic T‐cell lymphoma (AITL) is a rare form of NHL and usually presents in the late stage due to the atypical laboratory findings. Immunohistochemistry of the lymph node in AITL is characterized by positive CD2, CD3, CD4, CD10, CXCL‐13, PD1 often BCL‐6 and CD20 positive. Meshworks of follicular dendritic cells are seen outside follicles with CD21 and CD23 stains. EBV can be often positive as well. Autologous transplantation should be offered in the first remission as poor outcome is reported with anthracycline‐containing regimens.

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