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Angioimmunoblastic T‐cell lymphoma: a rare subtype of peripheral T‐cell lymphoma
Angioimmunoblastic T‐cell lymphoma (AITL) is a rare form of NHL and usually presents in the late stage due to the atypical laboratory findings. Immunohistochemistry of the lymph node in AITL is characterized by positive CD2, CD3, CD4, CD10, CXCL‐13, PD1 often BCL‐6 and CD20 positive. Meshworks of fo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889216/ https://www.ncbi.nlm.nih.gov/pubmed/29636953 http://dx.doi.org/10.1002/ccr3.1388 |
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author | Rai, Manoj Ponadka Bedi, Prabhjot Singh Marinas, Edwin B Khan, Nazia Naz S. |
author_facet | Rai, Manoj Ponadka Bedi, Prabhjot Singh Marinas, Edwin B Khan, Nazia Naz S. |
author_sort | Rai, Manoj Ponadka |
collection | PubMed |
description | Angioimmunoblastic T‐cell lymphoma (AITL) is a rare form of NHL and usually presents in the late stage due to the atypical laboratory findings. Immunohistochemistry of the lymph node in AITL is characterized by positive CD2, CD3, CD4, CD10, CXCL‐13, PD1 often BCL‐6 and CD20 positive. Meshworks of follicular dendritic cells are seen outside follicles with CD21 and CD23 stains. EBV can be often positive as well. Autologous transplantation should be offered in the first remission as poor outcome is reported with anthracycline‐containing regimens. |
format | Online Article Text |
id | pubmed-5889216 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-58892162018-04-10 Angioimmunoblastic T‐cell lymphoma: a rare subtype of peripheral T‐cell lymphoma Rai, Manoj Ponadka Bedi, Prabhjot Singh Marinas, Edwin B Khan, Nazia Naz S. Clin Case Rep Clinical Images Angioimmunoblastic T‐cell lymphoma (AITL) is a rare form of NHL and usually presents in the late stage due to the atypical laboratory findings. Immunohistochemistry of the lymph node in AITL is characterized by positive CD2, CD3, CD4, CD10, CXCL‐13, PD1 often BCL‐6 and CD20 positive. Meshworks of follicular dendritic cells are seen outside follicles with CD21 and CD23 stains. EBV can be often positive as well. Autologous transplantation should be offered in the first remission as poor outcome is reported with anthracycline‐containing regimens. John Wiley and Sons Inc. 2018-02-10 /pmc/articles/PMC5889216/ /pubmed/29636953 http://dx.doi.org/10.1002/ccr3.1388 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Images Rai, Manoj Ponadka Bedi, Prabhjot Singh Marinas, Edwin B Khan, Nazia Naz S. Angioimmunoblastic T‐cell lymphoma: a rare subtype of peripheral T‐cell lymphoma |
title | Angioimmunoblastic T‐cell lymphoma: a rare subtype of peripheral T‐cell lymphoma |
title_full | Angioimmunoblastic T‐cell lymphoma: a rare subtype of peripheral T‐cell lymphoma |
title_fullStr | Angioimmunoblastic T‐cell lymphoma: a rare subtype of peripheral T‐cell lymphoma |
title_full_unstemmed | Angioimmunoblastic T‐cell lymphoma: a rare subtype of peripheral T‐cell lymphoma |
title_short | Angioimmunoblastic T‐cell lymphoma: a rare subtype of peripheral T‐cell lymphoma |
title_sort | angioimmunoblastic t‐cell lymphoma: a rare subtype of peripheral t‐cell lymphoma |
topic | Clinical Images |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889216/ https://www.ncbi.nlm.nih.gov/pubmed/29636953 http://dx.doi.org/10.1002/ccr3.1388 |
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