The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive fibrotic lung disease for which there is no cure. Current therapeutics are only able to slow disease progression, therefore there is a need to explore alternative, novel treatment options. There is increasing evidence that...

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Detalles Bibliográficos
Autores principales: Roberts, Maxine J., Broome, Rebecca E., Kent, Toby C., Charlton, Steven J., Rosethorne, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889558/
https://www.ncbi.nlm.nih.gov/pubmed/29625570
http://dx.doi.org/10.1186/s12931-018-0759-2

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