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Identification and biosynthesis of thymidine hypermodifications in the genomic DNA of widespread bacterial viruses

Certain viruses of bacteria (bacteriophages) enzymatically hypermodify their DNA to protect their genetic material from host restriction endonuclease-mediated cleavage. Historically, it has been known that virion DNAs from the Delftia phage ΦW-14 and the Bacillus phage SP10 contain the hypermodified...

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Detalles Bibliográficos
Autores principales: Lee, Yan-Jiun, Dai, Nan, Walsh, Shannon E., Müller, Stephanie, Fraser, Morgan E., Kauffman, Kathryn M., Guan, Chudi, Corrêa, Ivan R., Weigele, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889632/
https://www.ncbi.nlm.nih.gov/pubmed/29555775
http://dx.doi.org/10.1073/pnas.1714812115

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