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Identification and biosynthesis of thymidine hypermodifications in the genomic DNA of widespread bacterial viruses
Certain viruses of bacteria (bacteriophages) enzymatically hypermodify their DNA to protect their genetic material from host restriction endonuclease-mediated cleavage. Historically, it has been known that virion DNAs from the Delftia phage ΦW-14 and the Bacillus phage SP10 contain the hypermodified...
Autores principales: | Lee, Yan-Jiun, Dai, Nan, Walsh, Shannon E., Müller, Stephanie, Fraser, Morgan E., Kauffman, Kathryn M., Guan, Chudi, Corrêa, Ivan R., Weigele, Peter R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889632/ https://www.ncbi.nlm.nih.gov/pubmed/29555775 http://dx.doi.org/10.1073/pnas.1714812115 |
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