Expansions, diversification, and interindividual copy number variations of AID/APOBEC family cytidine deaminase genes in lampreys

Cytidine deaminases of the AID/APOBEC family catalyze C-to-U nucleotide transitions in mRNA or DNA. Members of the APOBEC3 branch are involved in antiviral defense, whereas AID contributes to diversification of antibody repertoires in jawed vertebrates via somatic hypermutation, gene conversion, and...

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Detalles Bibliográficos
Autores principales: Holland, Stephen J., Berghuis, Lesley M., King, Justin J., Iyer, Lakshminarayan M., Sikora, Katarzyna, Fifield, Heather, Peter, Sarah, Quinlan, Emma M., Sugahara, Fumiaki, Shingate, Prashant, Trancoso, Inês, Iwanami, Norimasa, Temereva, Elena, Strohmeier, Christine, Kuratani, Shigeru, Venkatesh, Byrappa, Evanno, Guillaume, Aravind, L., Schorpp, Michael, Larijani, Mani, Boehm, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889659/
https://www.ncbi.nlm.nih.gov/pubmed/29555777
http://dx.doi.org/10.1073/pnas.1720871115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889659/
https://www.ncbi.nlm.nih.gov/pubmed/29555777
http://dx.doi.org/10.1073/pnas.1720871115

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