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Expansions, diversification, and interindividual copy number variations of AID/APOBEC family cytidine deaminase genes in lampreys
Cytidine deaminases of the AID/APOBEC family catalyze C-to-U nucleotide transitions in mRNA or DNA. Members of the APOBEC3 branch are involved in antiviral defense, whereas AID contributes to diversification of antibody repertoires in jawed vertebrates via somatic hypermutation, gene conversion, and...
Autores principales: | Holland, Stephen J., Berghuis, Lesley M., King, Justin J., Iyer, Lakshminarayan M., Sikora, Katarzyna, Fifield, Heather, Peter, Sarah, Quinlan, Emma M., Sugahara, Fumiaki, Shingate, Prashant, Trancoso, Inês, Iwanami, Norimasa, Temereva, Elena, Strohmeier, Christine, Kuratani, Shigeru, Venkatesh, Byrappa, Evanno, Guillaume, Aravind, L., Schorpp, Michael, Larijani, Mani, Boehm, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889659/ https://www.ncbi.nlm.nih.gov/pubmed/29555777 http://dx.doi.org/10.1073/pnas.1720871115 |
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