mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction

Mammalian/mechanistic target of rapamycin (mTOR) signaling controls cell growth, proliferation, and metabolism in dividing cells. Less is known regarding its function in postmitotic neurons in the adult brain. Here we created a conditional mTOR knockout mouse model to address this question. Using th...

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Detalles Bibliográficos
Autores principales: Liu, Dong, Stowie, Adam, de Zavalia, Nuria, Leise, Tanya, Pathak, Salil Saurav, Drewes, Lester R., Davidson, Alec J., Amir, Shimon, Sonenberg, Nahum, Cao, Ruifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889665/
https://www.ncbi.nlm.nih.gov/pubmed/29555746
http://dx.doi.org/10.1073/pnas.1721578115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889665/
https://www.ncbi.nlm.nih.gov/pubmed/29555746
http://dx.doi.org/10.1073/pnas.1721578115

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