Effect of the Antioxidant Lipoic Acid in Aortic Phenotype in a Marfan Syndrome Mouse Model

Marfan syndrome (MFS) cardiovascular manifestations such as aortic aneurysms and cardiomyopathy carry substantial morbidity/mortality. We investigated the effects of lipoic acid, an antioxidant, on ROS production and aortic remodeling in a MFS mgΔ(loxPneo) mouse model. MFS and WT (wild-type) 1-month...

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Detalles Bibliográficos
Autores principales: Guido, Maria C., Debbas, Victor, Salemi, Vera M., Tavares, Elaine R., Meirelles, Thayna, Araujo, Thaís L. S., Nolasco, Patricia, Ferreira-Filho, Julio C. A., Takimura, Celso K., Pereira, Lygia V., Laurindo, Francisco R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889865/
https://www.ncbi.nlm.nih.gov/pubmed/29765495
http://dx.doi.org/10.1155/2018/3967213

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