Optimum Antithrombotic Therapy in Patients Requiring Long-Term Anticoagulation and Undergoing Percutaneous Coronary Intervention

Management of patients on long-term anticoagulation requiring percutaneous coronary intervention is challenging. Triple therapy with oral anticoagulant and dual antiplatelet therapy is the standard of care. However, there is no strong evidence to support this strategy. There is emerging data regardi...

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Autores principales: Agarwal, Nayan, Mahtta, Dhruv, Rambarat, Cecil A., Elgendy, Islam, Mahmoud, Ahmed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889881/
https://www.ncbi.nlm.nih.gov/pubmed/29770334
http://dx.doi.org/10.1155/2018/5690640
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author Agarwal, Nayan
Mahtta, Dhruv
Rambarat, Cecil A.
Elgendy, Islam
Mahmoud, Ahmed N.
author_facet Agarwal, Nayan
Mahtta, Dhruv
Rambarat, Cecil A.
Elgendy, Islam
Mahmoud, Ahmed N.
author_sort Agarwal, Nayan
collection PubMed
description Management of patients on long-term anticoagulation requiring percutaneous coronary intervention is challenging. Triple therapy with oral anticoagulant and dual antiplatelet therapy is the standard of care. However, there is no strong evidence to support this strategy. There is emerging data regarding the safety and efficacy of dual therapy with oral anticoagulant and single antiplatelet therapy in these patients. In this comprehensive review we highlight available evidence regarding various antithrombotic regimens' efficacy and safety in patient with coronary artery disease undergoing percutaneous coronary intervention with long-term anticoagulation therapy requirements.
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spelling pubmed-58898812018-05-16 Optimum Antithrombotic Therapy in Patients Requiring Long-Term Anticoagulation and Undergoing Percutaneous Coronary Intervention Agarwal, Nayan Mahtta, Dhruv Rambarat, Cecil A. Elgendy, Islam Mahmoud, Ahmed N. Biomed Res Int Review Article Management of patients on long-term anticoagulation requiring percutaneous coronary intervention is challenging. Triple therapy with oral anticoagulant and dual antiplatelet therapy is the standard of care. However, there is no strong evidence to support this strategy. There is emerging data regarding the safety and efficacy of dual therapy with oral anticoagulant and single antiplatelet therapy in these patients. In this comprehensive review we highlight available evidence regarding various antithrombotic regimens' efficacy and safety in patient with coronary artery disease undergoing percutaneous coronary intervention with long-term anticoagulation therapy requirements. Hindawi 2018-03-25 /pmc/articles/PMC5889881/ /pubmed/29770334 http://dx.doi.org/10.1155/2018/5690640 Text en Copyright © 2018 Nayan Agarwal et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Agarwal, Nayan
Mahtta, Dhruv
Rambarat, Cecil A.
Elgendy, Islam
Mahmoud, Ahmed N.
Optimum Antithrombotic Therapy in Patients Requiring Long-Term Anticoagulation and Undergoing Percutaneous Coronary Intervention
title Optimum Antithrombotic Therapy in Patients Requiring Long-Term Anticoagulation and Undergoing Percutaneous Coronary Intervention
title_full Optimum Antithrombotic Therapy in Patients Requiring Long-Term Anticoagulation and Undergoing Percutaneous Coronary Intervention
title_fullStr Optimum Antithrombotic Therapy in Patients Requiring Long-Term Anticoagulation and Undergoing Percutaneous Coronary Intervention
title_full_unstemmed Optimum Antithrombotic Therapy in Patients Requiring Long-Term Anticoagulation and Undergoing Percutaneous Coronary Intervention
title_short Optimum Antithrombotic Therapy in Patients Requiring Long-Term Anticoagulation and Undergoing Percutaneous Coronary Intervention
title_sort optimum antithrombotic therapy in patients requiring long-term anticoagulation and undergoing percutaneous coronary intervention
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889881/
https://www.ncbi.nlm.nih.gov/pubmed/29770334
http://dx.doi.org/10.1155/2018/5690640
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