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AEG-1 Contributes to Metastasis in Hypoxia-Related Ovarian Cancer by Modulating the HIF-1alpha/NF-kappaB/VEGF Pathway

OBJECTIVE: Ovarian carcinoma represents one of the deadliest malignancies among female cancer patients. Astrocyte-elevated gene-1 (AEG-1) participates in the ontogenesis of multiple human malignant diseases. Here we evaluated AEG-1, hypoxia-inducible factor- (HIF-) 1α, nuclear factor kappa-light-cha...

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Detalles Bibliográficos
Autores principales: Yu, Xiaoyu, Wang, Yan, Qiu, Huilei, Song, Hongtao, Feng, Di, Jiang, Yang, Deng, Shuzhe, Meng, Hongxue, Geng, Jingshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889902/
https://www.ncbi.nlm.nih.gov/pubmed/29770329
http://dx.doi.org/10.1155/2018/3145689