Cargando…

AEG-1 Contributes to Metastasis in Hypoxia-Related Ovarian Cancer by Modulating the HIF-1alpha/NF-kappaB/VEGF Pathway

OBJECTIVE: Ovarian carcinoma represents one of the deadliest malignancies among female cancer patients. Astrocyte-elevated gene-1 (AEG-1) participates in the ontogenesis of multiple human malignant diseases. Here we evaluated AEG-1, hypoxia-inducible factor- (HIF-) 1α, nuclear factor kappa-light-cha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Xiaoyu, Wang, Yan, Qiu, Huilei, Song, Hongtao, Feng, Di, Jiang, Yang, Deng, Shuzhe, Meng, Hongxue, Geng, Jingshu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889902/ https://www.ncbi.nlm.nih.gov/pubmed/29770329 http://dx.doi.org/10.1155/2018/3145689

Ejemplares similares

NF-kappaB in Lung Tumorigenesis
por: Cai, Zhenjian, et al.
Publicado: (2011)

Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis.
por: Jue, D. M., et al.
Publicado: (1999)

NF-kappaB and cytokines in pancreatic acinar cells.
por: Kim, H, et al.
Publicado: (2000)

NF-kappaB: Two Sides of the Same Coin
por: Pires, Bruno R. B., et al.
Publicado: (2018)

An Update on the Multifaceted Role of NF-kappaB in Endometriosis
por: Liu, Yuanmeng, et al.
Publicado: (2022)

Recent insights into the role of NF-kappaB in ovarian carcinogenesis
por: Alvero, Ayesha B
Publicado: (2010)

NF-kappaB Signaling in Chronic Inflammatory Airway Disease
por: Schuliga, Michael
Publicado: (2015)

Bank1 and NF-kappaB as key regulators in anti-nucleolar antibody development
por: Alkaissi, Hammoudi, et al.
Publicado: (2018)

A reduced level of the long non-coding RNA SNHG8 activates the NF-kappaB pathway by releasing functional HIF-1alpha in a hypoxic inflammatory microenvironment
por: Wang, Chenxin, et al.
Publicado: (2022)

Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the Host
por: Cieniewicz, Brandon, et al.
Publicado: (2016)

NF-kappaB Regulates Redox Status in Breast Cancer Subtypes
por: Pires, Bruno R. B., et al.
Publicado: (2018)

Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macrophages by an NF-kappaB-dependent pathway
por: Lo, Susan ZY, et al.
Publicado: (2011)

Effects of decoy molecules targeting NF-kappaB transcription factors in Cystic fibrosis IB3–1 cells: Recruitment of NF-kappaB to the IL-8 gene promoter and transcription of the IL-8 gene
por: Finotti, Alessia, et al.
Publicado: (2012)

Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB
por: Solomon, Leigh A, et al.
Publicado: (2008)

In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells
por: Naamane, Najib, et al.
Publicado: (2007)

Expression of NF-kappaB and cytokines in chronic rejection of transplanted murine heart.
por: Lee, J. R., et al.
Publicado: (2001)

NF-kappaB Mediated Transcriptional Repression of Acid Modifying Hormone Gastrin
por: Datta De, Dipanjana, et al.
Publicado: (2013)

NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review
por: Shih, Ruey-Horng, et al.
Publicado: (2015)

NF-kappaB Is Involved in the Regulation of EMT Genes in Breast Cancer Cells
por: Pires, Bruno R. B., et al.
Publicado: (2017)

Piperlongumine Improves Lipopolysaccharide-Induced Amyloidogenesis by Suppressing NF-KappaB Pathway
por: Gu, Sun Mi, et al.
Publicado: (2018)

Cell-Type Targeted NF-kappaB Inhibition for the Treatment of Inflammatory Diseases
por: Sehnert, Bettina, et al.
Publicado: (2020)

Dihydromyricetin Attenuates Inflammation through TLR4/NF-kappaB Pathway
por: Jing, Nianshui, et al.
Publicado: (2019)

AEG-1 is associated with hypoxia-induced hepatocellular carcinoma chemoresistance via regulating PI3K/AKT/HIF-1alpha/MDR-1 pathway
por: Xie, Yong, et al.
Publicado: (2016)

Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma
por: Yang, David T, et al.
Publicado: (2008)

The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB
Publicado: (1996)

Aberrant NF-KappaB Expression in Autism Spectrum Condition: A Mechanism for Neuroinflammation
por: Young, Adam M. H., et al.
Publicado: (2011)

The Receptor Tyrosine Kinase FGFR4 Negatively Regulates NF-kappaB Signaling
por: Drafahl, Kristine A., et al.
Publicado: (2010)

The functional genomic response of developing embryonic submandibular glands to NF-kappaB inhibition
por: Melnick, Michael, et al.
Publicado: (2001)

A functional genomics screen for microRNA regulators of NF-kappaB signaling
por: Olarerin-George, Anthony O, et al.
Publicado: (2013)

Inhibition of astroglial NF-kappaB enhances oligodendrogenesis following spinal cord injury
por: Bracchi-Ricard, Valerie, et al.
Publicado: (2013)

TWEAK/Fn14 and Non-Canonical NF-kappaB Signaling in Kidney Disease
por: Poveda, Jonay, et al.
Publicado: (2013)

NF-kappaB activation: Tax sumoylation is out, but what about Tax ubiquitination?
por: Xiao, Gutian
Publicado: (2012)

NF-KappaB in Long-Term Memory and Structural Plasticity in the Adult Mammalian Brain
por: Kaltschmidt, Barbara, et al.
Publicado: (2015)

Role of NF-kappaB2-p100 in regulatory T cell homeostasis and activation
por: Dhar, Atika, et al.
Publicado: (2019)

HIF‐1α binding to AEG‐1 promoter induced upregulated AEG‐1 expression associated with metastasis in ovarian cancer
por: Zhao, Ting, et al.
Publicado: (2017)

A cell type-specific enhancer in the human B7.1 gene regulated by NF- kappaB
Publicado: (1996)

The preservative polyquaternium-1 increases cytoxicity and NF-kappaB linked inflammation in human corneal epithelial cells
por: Paimela, Tuomas, et al.
Publicado: (2012)

Bmi-1 promotes the aggressiveness of glioma via activating the NF-kappaB/MMP-9 signaling pathway
por: Jiang, Lili, et al.
Publicado: (2012)

MicroRNA-9 regulates the development of knee osteoarthritis through the NF-kappaB1 pathway in chondrocytes
por: Gu, Ronghe, et al.
Publicado: (2016)

Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression
por: Piccagli, Laura, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_18g5l4irijclcki79tkqetqpps