Ketogenic Diet Improves Brain Ischemic Tolerance and Inhibits NLRP3 Inflammasome Activation by Preventing Drp1-Mediated Mitochondrial Fission and Endoplasmic Reticulum Stress

Background: Neuroprotective effects of ketogenic diets (KD) have been reported in stroke models, and nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome has also been implicated in the pathogenesis of stroke. This study aimed to investigate the effects of KD on NLRP3 inflamm...

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Detalles Bibliográficos
Autores principales: Guo, Min, Wang, Xun, Zhao, Yanxin, Yang, Qi, Ding, Hongyan, Dong, Qiang, Chen, Xingdong, Cui, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890101/
https://www.ncbi.nlm.nih.gov/pubmed/29662437
http://dx.doi.org/10.3389/fnmol.2018.00086

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