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The Length of SNCA Rep1 Microsatellite May Influence Cognitive Evolution in Parkinson’s Disease

BACKGROUND: Alpha-synuclein is a constituent of Lewy bodies and mutations of its gene cause familial Parkinson’s disease (PD). A previous study showed that a variant of the alpha-synuclein gene (SNCA), namely the 263 bp allele of Rep1 was associated with faster motor progression in PD. On the contra...

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Detalles Bibliográficos
Autores principales:	Corrado, Lucia, De Marchi, Fabiola, Tunesi, Sara, Oggioni, Gaia Donata, Carecchio, Miryam, Magistrelli, Luca, Tesei, Silvana, Riboldazzi, Giulio, Di Fonzo, Alessio, Locci, Clarissa, Trezzi, Ilaria, Zangaglia, Roberta, Cereda, Cristina, D’Alfonso, Sandra, Magnani, Corrado, Comi, Giacomo P., Bono, Giorgio, Pacchetti, Claudio, Cantello, Roberto, Goldwurm, Stefano, Comi, Cristoforo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890103/ https://www.ncbi.nlm.nih.gov/pubmed/29662465 http://dx.doi.org/10.3389/fneur.2018.00213

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