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Activation of the NLRP3 Inflammasome Pathway by Uropathogenic Escherichia coli Is Virulence Factor-Dependent and Influences Colonization of Bladder Epithelial Cells

The NLRP3 inflammasome and IL-1β release have recently been suggested to be important for the progression of urinary tract infection (UTI). However, much is still unknown regarding the interaction of UPEC and the NLRP3 inflammasome. The purpose of this study was to elucidate what virulence factors u...

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Detalles Bibliográficos
Autores principales: Demirel, Isak, Persson, Alexander, Brauner, Annelie, Särndahl, Eva, Kruse, Robert, Persson, Katarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890162/
https://www.ncbi.nlm.nih.gov/pubmed/29662840
http://dx.doi.org/10.3389/fcimb.2018.00081