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A Novel EphA2 Inhibitor Exerts Beneficial Effects in PI-IBS in Vivo and in Vitro Models via Nrf2 and NF-κB Signaling Pathways

Though the detailed pathological mechanism of post-infectious irritable bowel syndrome (PI-IBS) remains unclear, accumulating evidence indicates that oxidative stress and inflammation are implicated in the process of PI-IBS. Oxidative stress and inflammation are regulated by Nrf2 and NF-κB signaling...

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Detalles Bibliográficos
Autores principales: Zeng, Li, Li, Kaixue, Wei, Hong, Hu, Jingjing, Jiao, Lu, Yu, Shaoyong, Xiong, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890185/
https://www.ncbi.nlm.nih.gov/pubmed/29662452
http://dx.doi.org/10.3389/fphar.2018.00272

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