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IL-15 Promotes Polyfunctional NK Cell Responses to Influenza by Boosting IL-12 Production

IL-15 is a key regulator of NK cell maintenance and proliferation and synergizes with other myeloid cell–derived cytokines to enhance NK cell effector function. At low concentrations, trans-presentation of IL-15 by dendritic cells can activate NK cells, whereas at higher concentrations it can act di...

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Detalles Bibliográficos
Autores principales:	Wagstaffe, Helen R., Nielsen, Carolyn M., Riley, Eleanor M., Goodier, Martin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2018
Materias:	Innate Immunity and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890538/ https://www.ncbi.nlm.nih.gov/pubmed/29491009 http://dx.doi.org/10.4049/jimmunol.1701614

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