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Conjunctival papilloma: Clinical features, outcome, and factors related to recurrence
PURPOSE: The purpose of the study was to evaluate the clinical features, treatment, and outcome of patients with conjunctival papilloma. MATERIALS AND METHODS: Twenty-two patients (22 eyes) with biopsy-proven conjunctival papilloma between January 2005 and January 2015 in a tertiary medical center w...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890578/ https://www.ncbi.nlm.nih.gov/pubmed/29675344 http://dx.doi.org/10.4103/tjo.tjo_2_18 |
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author | Huang, Yi-Ming Huang, Yu-Yun Yang, Hsin-Yu Tsai, Chieh-Chih Yu, Wei-Kuang Kao, Shu-Ching Kau, Hui-Chuan Liu, Catherine Jui-Ling |
author_facet | Huang, Yi-Ming Huang, Yu-Yun Yang, Hsin-Yu Tsai, Chieh-Chih Yu, Wei-Kuang Kao, Shu-Ching Kau, Hui-Chuan Liu, Catherine Jui-Ling |
author_sort | Huang, Yi-Ming |
collection | PubMed |
description | PURPOSE: The purpose of the study was to evaluate the clinical features, treatment, and outcome of patients with conjunctival papilloma. MATERIALS AND METHODS: Twenty-two patients (22 eyes) with biopsy-proven conjunctival papilloma between January 2005 and January 2015 in a tertiary medical center were retrospectively reviewed. Clinical profiles, treatment, outcome, and factors related to recurrence were evaluated. RESULTS: There were 16 males (73%) and 6 females (27%), with a mean age of 47 years. The most common location of conjunctival papilloma was the caruncle (43%), followed by palpebral conjunctiva (29%), bulbar conjunctiva (14%), and fornix (14%). Recurrence developed in five patients (22.7%). The risk of postoperative recurrence was significantly related to the presence of bulbar conjunctival papilloma with corneal involvement (P = 0.043) and surgical excision alone (P = 0.039). One case with multiple recurrences developed nonkeratinizing carcinoma. Two young females developed conjunctival papilloma even after receiving human papillomavirus vaccinations. CONCLUSION: The recurrence of conjunctival papilloma is not uncommon, especially for those patients underwent surgical excision alone. Surgical excision with adjunctive therapy and long-term follow-up is rational for the treatment of conjunctival papilloma. |
format | Online Article Text |
id | pubmed-5890578 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-58905782018-04-19 Conjunctival papilloma: Clinical features, outcome, and factors related to recurrence Huang, Yi-Ming Huang, Yu-Yun Yang, Hsin-Yu Tsai, Chieh-Chih Yu, Wei-Kuang Kao, Shu-Ching Kau, Hui-Chuan Liu, Catherine Jui-Ling Taiwan J Ophthalmol Original Article PURPOSE: The purpose of the study was to evaluate the clinical features, treatment, and outcome of patients with conjunctival papilloma. MATERIALS AND METHODS: Twenty-two patients (22 eyes) with biopsy-proven conjunctival papilloma between January 2005 and January 2015 in a tertiary medical center were retrospectively reviewed. Clinical profiles, treatment, outcome, and factors related to recurrence were evaluated. RESULTS: There were 16 males (73%) and 6 females (27%), with a mean age of 47 years. The most common location of conjunctival papilloma was the caruncle (43%), followed by palpebral conjunctiva (29%), bulbar conjunctiva (14%), and fornix (14%). Recurrence developed in five patients (22.7%). The risk of postoperative recurrence was significantly related to the presence of bulbar conjunctival papilloma with corneal involvement (P = 0.043) and surgical excision alone (P = 0.039). One case with multiple recurrences developed nonkeratinizing carcinoma. Two young females developed conjunctival papilloma even after receiving human papillomavirus vaccinations. CONCLUSION: The recurrence of conjunctival papilloma is not uncommon, especially for those patients underwent surgical excision alone. Surgical excision with adjunctive therapy and long-term follow-up is rational for the treatment of conjunctival papilloma. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5890578/ /pubmed/29675344 http://dx.doi.org/10.4103/tjo.tjo_2_18 Text en Copyright: © 2018 Taiwan J Ophthalmol http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Huang, Yi-Ming Huang, Yu-Yun Yang, Hsin-Yu Tsai, Chieh-Chih Yu, Wei-Kuang Kao, Shu-Ching Kau, Hui-Chuan Liu, Catherine Jui-Ling Conjunctival papilloma: Clinical features, outcome, and factors related to recurrence |
title | Conjunctival papilloma: Clinical features, outcome, and factors related to recurrence |
title_full | Conjunctival papilloma: Clinical features, outcome, and factors related to recurrence |
title_fullStr | Conjunctival papilloma: Clinical features, outcome, and factors related to recurrence |
title_full_unstemmed | Conjunctival papilloma: Clinical features, outcome, and factors related to recurrence |
title_short | Conjunctival papilloma: Clinical features, outcome, and factors related to recurrence |
title_sort | conjunctival papilloma: clinical features, outcome, and factors related to recurrence |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890578/ https://www.ncbi.nlm.nih.gov/pubmed/29675344 http://dx.doi.org/10.4103/tjo.tjo_2_18 |
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