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Progressive neurodegeneration following spinal cord injury: Implications for clinical trials

OBJECTIVE: To quantify atrophy, demyelination, and iron accumulation over 2 years following acute spinal cord injury and to identify MRI predictors of clinical outcomes and determine their suitability as surrogate markers of therapeutic intervention. METHODS: We assessed 156 quantitative MRI dataset...

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Detalles Bibliográficos
Autores principales: Ziegler, Gabriel, Grabher, Patrick, Thompson, Alan, Altmann, Daniel, Hupp, Markus, Ashburner, John, Friston, Karl, Weiskopf, Nikolaus, Curt, Armin, Freund, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890610/
https://www.ncbi.nlm.nih.gov/pubmed/29514946
http://dx.doi.org/10.1212/WNL.0000000000005258