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Clinical value of neurofilament and phospho-tau/tau ratio in the frontotemporal dementia spectrum

OBJECTIVE: To examine the clinical value of neurofilament light chain (NfL) and the phospho-tau/total tau ratio (p/t-tau) across the entire frontotemporal dementia (FTD) spectrum in a large, well-defined cohort. METHODS: CSF NfL and p/t-tau levels were studied in 361 patients with FTD: 179 behaviora...

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Detalles Bibliográficos
Autores principales: Meeter, Lieke H.H., Vijverberg, Everard G., Del Campo, Marta, Rozemuller, Annemieke J.M., Donker Kaat, Laura, de Jong, Frank Jan, van der Flier, Wiesje M., Teunissen, Charlotte E., van Swieten, John C., Pijnenburg, Yolande A.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890612/
https://www.ncbi.nlm.nih.gov/pubmed/29514947
http://dx.doi.org/10.1212/WNL.0000000000005261