Cargando…
A novel variant in GLIS3 is associated with osteoarthritis
OBJECTIVES: Osteoarthritis (OA) is a complex disease, but its genetic aetiology remains poorly characterised. To identify novel susceptibility loci for OA, we carried out a genome-wide association study (GWAS) in individuals from the largest UK-based OA collections to date. METHODS: We carried out a...
Autores principales: | Casalone, Elisabetta, Tachmazidou, Ioanna, Zengini, Eleni, Hatzikotoulas, Konstantinos, Hackinger, Sophie, Suveges, Daniel, Steinberg, Julia, Rayner, Nigel William, Wilkinson, Jeremy Mark, Panoutsopoulou, Kalliope, Zeggini, Eleftheria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890630/ https://www.ncbi.nlm.nih.gov/pubmed/29436472 http://dx.doi.org/10.1136/annrheumdis-2017-211848 |
Ejemplares similares
-
Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis
por: Steinberg, Julia, et al.
Publicado: (2018) -
In search of low-frequency and rare variants affecting complex traits
por: Panoutsopoulou, Kalliope, et al.
Publicado: (2013) -
Advances in osteoarthritis genetics
por: Panoutsopoulou, Kalliope, et al.
Publicado: (2013) -
No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls
por: Hudson, Gavin, et al.
Publicado: (2013) -
Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis
por: Zengini, Eleni, et al.
Publicado: (2018)