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Hypertonic Saline Alleviates Brain Edema After Traumatic Brain Injury via Downregulation of Aquaporin 4 in Rats

BACKGROUND: Hypertonic saline (HS) has been successfully used for treatment of various forms of brain edema. Decreased expression of aquaporin (AQP)4 and pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α and interleukin (IL)-1β have been linked to edema pathogenesis. This study examin...

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Detalles Bibliográficos
Autores principales:	Yin, Jian, Zhang, Haixiao, Chen, Huai, Lv, Qingping, Jin, Xuhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890824/ https://www.ncbi.nlm.nih.gov/pubmed/29600800 http://dx.doi.org/10.12659/MSM.907212

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